Along with rest, strengthening exercises and non-steroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs) represent the reference treatment for RA. Under this name there is a group of drugs potentially capable of influencing the evolution of rheumatic disease, unlike NSAIDs, whose action is eminently symptomatic (relief of pain and reduction of inflammatory expression).
Methotrexate (MTX) is the DMARD most used in the management of RA Flekosteel. It is a folic acid antagonist used in the treatment of certain neoplastic diseases.
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